{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328176/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Rattus norvegicus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328176"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-Cell RNA Sequencing Reveals Yiqi Huayu Jiedu Formula Alleviates Acute Respiratory Distress Syndrome Through Regulation of Macrophage Chemotaxis","description":"Integrated network pharmacology, single-cell RNA sequencing, and experimental analyses revealed that Yiqi Huayu Jiedu Formula (YQHYJDF) protects lung tissue by inhibiting macrophage chemotaxis and neutrophil recruitment through suppression of proinflammatory cytokines IL-6, IL-1β, and TNF-α, PI3K/AKT, MAPK, and NF-κB signaling, and downregulation of chemokines CCL2, CCL7, and CCL12.","dates":{"publication":"2026/04/16"},"accession":"GSE328176","cross_references":{"GSM":["GSM9674460","GSM9674462","GSM9674461","GSM9674464","GSM9674463","GSM9674466","GSM9674465","GSM9674467","GSM9674459"],"GPL":["25947"],"GSE":["328176"],"taxon":["Rattus norvegicus"]}}