GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328230/primaryOK200GenomicsHomo sapiensGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328230GEOGSEfalseATAC-seq profiling reveals that KLF2 regulates chromatin accessibility programs in HCCKrüppel-like factor 2 (KLF2) is a tumor-suppressive transcription factor implicated in the regulation of epithelial-mesenchymal plasticity in hepatocellular carcinoma (HCC). In this study, we performed ATAC-seq in HCCLM3 human HCC cells with or without KLF2 overexpression to characterize KLF2-associated changes in chromatin accessibility. Comparative analysis was used to identify differentially accessible chromatin regions and to investigate how KLF2 affects the transcriptional programs associated with Hippo/YAP signaling and EMT/pEMT-related cell plasticity.2026/04/21GSE328230GSM9675393GSM9675392GSM9675394GSM967539124676328230Homo sapiens