{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328244/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328244"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"COL1A1-Enhanced CD44/SLC7A11 Interaction and Cystine Uptake Result in CD34+ Foam-Like Macrophage Accumulation in Transplant Arteriosclerosis-Spatial Transcriptomic dataset","description":"Chronic transplant arteriosclerosis is a major cause of long-term graft failure. To investigate the cellular and molecular mechanisms underlying vascular remodeling, we performed integrated transcriptomic analyses including single-cell RNA-seq and Stereo-seq spatial transcriptomics in human chronic allograft vasculopathy specimens and mouse vascular allograft models. These data support the identification of inflammatory foam-like macrophages and their association with COL1A1-CD44-SLC7A11 signaling and cystine uptake.","dates":{"publication":"2026/09/10"},"accession":"GSE328244","cross_references":{"GSM":["GSM9675942","GSM9675941","GSM9675944","GSM9675945"],"GPL":["28330"],"GSE":["328244"],"taxon":["Mus musculus"],"PMID":["[42549511]"]}}