{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328395/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Methylation profiling"],"species":["Rattus norvegicus"],"gds_type":["Methylation profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328395"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"High intrinsic aerobic capacity shapes a distinct epigenetic profile in the aged rat brain","description":"Aging is accompanied by progressive decline in brain function, and aerobic fitness is thought to influence brain health. To examine whether intrinsic exercise capacity is associated with a distinct brain molecular phenotype in aging, we profiled hippocampal DNA methylation by reduced representation bisulfite sequencing (RRBS) in aged selectively bred rats with high or low intrinsic aerobic capacity.","dates":{"publication":"2026/07/12"},"accession":"GSE328395","cross_references":{"GSM":["GSM9682169","GSM9682167","GSM9682168","GSM9682165","GSM9682166","GSM9682163","GSM9682164","GSM9682161","GSM9682162","GSM9682170"],"GPL":["18694"],"GSE":["328395"],"taxon":["Rattus norvegicus"],"PMID":["[42444584]"]}}