{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328540/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Rattus norvegicus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328540"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Full length transcriptome sequencing of rat abdominal aorta primary EC","description":"MicroRNAs are well established as key regulators of cellular function and viability. A growing body of evidence indicates that multiple miRNAs are involved in the formation and rupture of IAs. MicroRNA-337-3p (miR-337-3p), in particular, has been implicated in the pathogenesis of diverse conditions—including tissue injury, osteoarthritis, and malignancies—by modulating cellular proliferation, fundamental biological processes, and oxidative stress-induced inflammatory responses. The abdominal aorta was excised from rats, with tissue segments everted to reveal the endothelium. Cultured endothelial cells (ECs) were transfected with 100 nM hsa-miR-337-3p inhibitor. RNA sequencing was performed to map the genetic differences lining between the WT and miRNA-337-3p-/- EC.","dates":{"publication":"2026/04/28"},"accession":"GSE328540","cross_references":{"GSM":["GSM9684953","GSM9684952","GSM9684951","GSM9684950","GSM9684949","GSM9684948"],"GPL":["33549"],"GSE":["328540"],"taxon":["Rattus norvegicus"]}}