GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328648/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328648GEOGSEfalseInvestigation of gene expression in human brain samplesAlzheimer's disease (AD) is a progressive neurodegenerative disease characterized by a gradual decline in neuronal activity, which affects memory and thinking. As it progresses, it can interfere with daily life, and it can eventually lead to death. AD accounts for approximately 60-70% of dementia cases and is particularly prevalent in the elderly. However, the gene regulatory mechanism for AD development in human brain tissues is still unclear. To deepen our understanding of the molecular mechanims involved in this cognitive decline, we conducted RNA-sequencing (RNA-seq) on six brain tissues from both control (Ct) without dementia and AD patients to analyze differentially expressed genes (DEGs) between Ct and AD brains.2026/09/09GSE328648GSM9686617GSM9686618GSM9802734GSM9686619GSM9686620GSM9686621GSM968662234284328648Homo sapiens