GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328693/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328693GEOGSEfalseRNA-seq analysis of FACS-sorted pre-metastatic lung endothelial cells reveal transcriptional programs regulated by cisplatin and FAK in the pre-metastatic lungThis study investigates the mechanisms underlying DNA-damage driven vascular endothelial-cell senescence regulated by EC-FAK and its role in lung cancer metastasis. RNA-seq analysis has been performed FACS-sorted pre-metastatic lung endothelial cells to identify FAK-regulated transcriptomic changes due to DNA- damaging therapy in tumour burdened and non-tumour burdened mice (comparisons between Cre-negative ECFAK WT mice with Cre-positive ECFAK KO mice in Cisplatin treated samples.2026/09/09GSE328693GSM9687470GSM9687450GSM9687430GSM9687452GSM9687454GSM9687432GSM9687456GSM9687434GSM9687457GSM9687436GSM9687459GSM9687438GSM9687439GSM9687461GSM9687463GSM9687441GSM9687465GSM9687443GSM9687466GSM9687445GSM9687423GSM9687468GSM9687447GSM9687425GSM9687448GSM9687427GSM968742924247328693Mus musculus[42687863]