GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329157/primary200OKTranscriptomicsCaenorhabditis elegansExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329157GEOGSEfalseRNA-seq profiling of L4-stage Caenorhabditis elegans exposed to AO168=O at environmentally relevant concentrationsTris(2,4-di-tert-butylphenyl) phosphate (AO168=O) is an emerging organophosphate contaminant derived from plastic antioxidants and widely detected in soils. To investigate its chronic biological effects, synchronized Caenorhabditis elegans were exposed to AO168=O in agar-based NGM medium and sampled at the L4 stage for transcriptomic analysis. Bulk RNA-seq was performed on control and AO168=O-treated worms at 400, 2000, and 10000 ng/g, with three biological replicates per group. The dataset was generated to characterize transcriptional responses associated with developmental restriction and IIS/DAF-16-related stress-responsive pathways.2026/06/01GSE329157GSM9698408GSM9698407GSM9698406GSM9698405GSM9698404GSM9698403GSM9698402GSM9698401GSM9698400GSM9698410GSM9698399GSM969840925147329157Caenorhabditis elegans