{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329263/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329263"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic Profiling of Thyroid Eye Disease Orbital Fibroblasts","description":"This project aims to define the persistent transcriptomic alterations in orbital fibroblasts (OFs) derived from patients with thyroid eye disease (TED) compared to non-TED OF controls. Primary OFs were isolated from orbital connective tissue and expanded in vitro under standardized conditions. We performed high-depth RNA sequencing on these cells to characterize the differential expression of genes involved in extracellular matrix remodeling, inflammatory signaling, and metabolic activation. This dataset provides a comprehensive resource for identifying the molecular drivers of orbital remodeling in the context of TED.","dates":{"publication":"2026/08/10"},"accession":"GSE329263","cross_references":{"GSM":["GSM9700352","GSM9700351","GSM9700354","GSM9700353","GSM9700356","GSM9700355","GSM9700358","GSM9700357","GSM9700349","GSM9700359","GSM9700350"],"GPL":["30173"],"GSE":["329263"],"taxon":["Homo sapiens"]}}