GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329263/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329263GEOGSEfalseTranscriptomic Profiling of Thyroid Eye Disease Orbital FibroblastsThis project aims to define the persistent transcriptomic alterations in orbital fibroblasts (OFs) derived from patients with thyroid eye disease (TED) compared to non-TED OF controls. Primary OFs were isolated from orbital connective tissue and expanded in vitro under standardized conditions. We performed high-depth RNA sequencing on these cells to characterize the differential expression of genes involved in extracellular matrix remodeling, inflammatory signaling, and metabolic activation. This dataset provides a comprehensive resource for identifying the molecular drivers of orbital remodeling in the context of TED.2026/08/10GSE329263GSM9700352GSM9700351GSM9700354GSM9700353GSM9700356GSM9700355GSM9700358GSM9700357GSM9700349GSM9700359GSM970035030173329263Homo sapiens