{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329565/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329565"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Gene expression profiling by RNA-Seq analysis of mice carrying an inner-ear conditional knockout of Esrrg.","description":"Estrogen-related receptor gamma (ESRRG), an orphan nuclear receptor with structural homology to the classical estrogen receptors, is widely recognised as a key metabolic regulator. Clinical studies have suggested a link between ESRRG and auditory function; however, the biological mechanisms through which ESRRG contributes to hearing remain largely unknown. Here, we report the results of comparative transcriptome profiling by RNA-Seq as part of our characterisation of the auditory phenotype in mice carrying a newly generated conditional knockout of Esrrg in the inner ear (Esrrgfl/fl;Sox10-Cre).","dates":{"publication":"2026/05/08"},"accession":"GSE329565","cross_references":{"GSM":["GSM9706478","GSM9706479","GSM9706474","GSM9706475","GSM9706476","GSM9706477","GSM9706470","GSM9706471","GSM9706472","GSM9706473"],"GPL":["24247"],"GSE":["329565"],"taxon":["Mus musculus"]}}