GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329568/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329568GEOGSEfalseTranscriptomic of Visceral Adipose Tissue in HFD-induced obesity: evaluation of ResveratrolVisceral adipose tissue (VAT) expansion during the development of obesity is a hallmark of metabolic syndrome, characterized by hypoxia, oxidative stress, and a shift toward a pro-inflammatory secretome. This series examines the transcriptomic profile of VAT in male C57BL/6 mice subjected to long-term obesity induced by a high-fat diet (HFD, 60% of kcal from fat). To investigate new therapeutic avenues, we evaluated the impact of daily resveratrol administration (2.25 mg/kg) for 28 days, beginning at week 16 of life (8 weeks on the HFD diet). Using a transcriptomic approach (RNA-seq), we mapped the expression changes associated with the transition from healthy to dysfunctional adipose tissue. This study provides a detailed molecular resource for understanding how obesity-induced adipocyte stress can be attenuated by natural bioactives.2026/05/04GSE329568GSM9706496GSM9706497GSM9706493GSM9706494GSM970649524247329568Mus musculus