GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329765/primaryOK200Transcriptomics Cavia porcellusHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329765GEOGSEfalsePichinde virus models intrauterine infection by hemorrhagic fever-causing arenavirusesArenaviruses infection during pregnancy can cause severe maternal disease, congenital infection, and/or fetal demise. Little is known about the pathogenesis of this family of viruses in the placenta because many are endemic in resource-poor regions and must be studied in high containment laboratories. Pichinde virus (PICV) is a nonpathogenic arenavirus that causes hemorrhagic fever-like disease in guinea pigs. In this study, we sought to assess whether PICV replicates in human trophoblasts and how infection affected pregnant guinea pigs. RNA-sequencing was done on PICV-infected human trophoblast stem cells and samples of placenta and decidua collected from infected and control pregnant guinea pigs.2026/09/19GSE329765GSM9710829GSM9710828GSM9710838GSM9710837GSM9710836GSM9710835GSM9710834GSM9710833GSM9710832GSM9710831GSM9710830GSM9710819GSM9710818GSM9710839GSM9710817GSM9710827GSM9710826GSM9710848GSM9710847GSM9710825GSM9710846GSM9710824GSM9710845GSM9710823GSM9710844GSM9710822GSM9710821GSM9710843GSM9710842GSM9710820GSM9710841GSM97108402843724676329765 Cavia porcellusHomo sapiens