{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329766/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329766"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic profiling of BAZ1A-AS1 and BAZ1A knockdown in human vascular smooth muscle cells and rhabdomyoblasts","description":"BAZ1A-AS1 is a novel human-specific long non-coding RNA upregulated during neointima proliferation in human saphenous veins. To elucidate the transcriptional programs regulated by BAZ1A-AS1 and its cis-regulatory gene BAZ1A, we performed bulk RNA-seq on human saphenous vein smooth muscle cells (HSVSMCs) with BAZ1A-AS1 knockdown (LNA gapmeR ASO) and rhabdomyoblast (RD) cells with BAZ1A knockdown (siRNA) under UV exposure. Differential expression analysis revealed convergent suppression of proliferative, inflammatory, and stress-response transcriptional programs across both knockdowns, supporting a shared regulatory axis.","dates":{"publication":"2026/07/01"},"accession":"GSE329766","cross_references":{"GSM":["GSM9710849","GSM9710859","GSM9710858","GSM9710857","GSM9710856","GSM9710855","GSM9710854","GSM9710853","GSM9710852","GSM9710851","GSM9710850","GSM9710860"],"GPL":["16791"],"GSE":["329766"],"taxon":["Homo sapiens"]}}