{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329905/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329905"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"snRNA-seq profiling of the ascending aorta and aortic arch from male and female Wnt1-Cre;Rosa26-mTmG mice","description":"Vascular smooth muscle cells (VSMCs) in the ascending aorta and aortic arch arise from two distinct embryonic origins: the second heart field (SHF) and the cardiac neural crest (CNC). Whether these populations exhibit sex-dependent differences remains unknown. In this study, we generated Wnt1-Cre/Rosa26-mTmG lineage-tracing mice and performed single-nucleus RNA sequencing using the ascending aortae and aortic arch from both sexes. This study revealed the differential expression of VSMCs from different embryonic origin in both sexes.","dates":{"publication":"2026/05/15"},"accession":"GSE329905","cross_references":{"GSM":["GSM9712942","GSM9712943"],"GPL":["24247"],"GSE":["329905"],"taxon":["Mus musculus"]}}