GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE330nnn/GSE330450/primaryOK200TranscriptomicsMacaca fascicularisExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE330450GEOGSEfalseThe single-nucleus RNA-seq of AAV-Abeta42 injected hippocampus of crab-eating macaqueIn our previous work, we found that hippocampal injection of AAV-Aβ42 induced robust Aβ deposition, increased abnormal phosphorylated tau (pTau) pathology, and neurodegeneration in the aged hippocampus, but not in young monkeys. To investigate the mechanisms underlying this age-dependent difference, we performed single-nucleus RNA sequencing (snRNA-seq) on monkeys at two developmental stages.2026/05/11GSE330450GSM9726487GSM9726476GSM9726477GSM9726478GSM9726479GSM9726480GSM9726481GSM9726482GSM9726483GSM9726484GSM9726485GSM972648624953330450Macaca fascicularis