GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE330nnn/GSE330634/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE330634GEOGSEfalseStudy on the Molecular Mechanism of BMP8B in Regulating Trophoblast Cell Function: A Transcriptomic Analysis Based on RNA-seqThe regulation of trophoblast cell function plays a central role in placental development and pregnancy maintenance. As a member of the bone morphogenetic protein family, BMP8B has been demonstrated to participate in regulating the migration, invasion, and differentiation of trophoblast cells. To deeply elucidate the specific molecular pathways by which BMP8B regulates trophoblast cell function, this study employed RNA sequencing technology to systematically analyze the transcriptomic differences between HTR8/SVneo cells treated with BMP8B for 24 hours and untreated control cells. Through screening of differentially expressed genes, functional enrichment analysis, and mining of key signaling pathways, we aim to reveal the downstream regulatory network of BMP8B in trophoblast cells, providing a molecular basis for understanding the pathogenesis of placenta-related diseases.2026/05/16GSE330634GSM9729589GSM9729590GSM9729584GSM9729583GSM9729586GSM9729585GSM9729588GSM972958724676330634Homo sapiens