{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE330nnn/GSE330657/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE330657"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Activation of tumor-specific CD8+ T cells prior to radiopharmaceutical therapy improves anti-tumor response","description":"Previously, we found that the presence and activation of tumor-specific CD8+ T cells prior to radiopharmaceutical therapy (RPT), 90Y-NM600, enhanced anti-tumor responses. Here, we aimed to evaluate changes in the tumor immune microenvironment after E.G7-OVA tumor-bearing mice received adoptive transfer of naïve OT-I CD8+ T cells, followed by a DNA vaccine, and 90Y-NM600. Tumors were collected 7 and 14 days following 90Y-NM600, isolated total RNA, and performed gene expression analysis using the nCounter Mouse Immune Exhaustion Panel on the nCounter MAX system.","dates":{"publication":"2026/06/19"},"accession":"GSE330657","cross_references":{"GSM":["GSM9729951","GSM9729940","GSM9729950","GSM9729942","GSM9729941","GSM9729944","GSM9729943","GSM9729946","GSM9729945","GSM9729948","GSM9729937","GSM9729947","GSM9729939","GSM9729938","GSM9729949"],"GPL":["32403"],"GSE":["330657"],"taxon":["Mus musculus"]}}