GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE330nnn/GSE330958/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE330958GEOGSEfalseLeveraging TNFR2 for antitumour immunity: Treg depletion and myeloid reprogramming versus T cell costimulationWe conducted single-cell RNA sequencing using the 10x Genomics Chromium Next-GEM Flex protocol to investigate the mechanism of action of two TNFR2-targeting antibodies—one ligand-blocking and the other agonistic. Our goal was to assess their anti-cancer potential in comparison to established immune checkpoint inhibitors, anti-PD1 and anti-CTLA4. These studies provide new insights and role of TNFR2 as a therapeutic target in cancer.2026/07/09GSE330958GSM9736509GSM9736507GSM9736508GSM9736516GSM9736517GSM9736514GSM9736515GSM9736512GSM9736513GSM9736510GSM973651124247330958Mus musculus[42466984]