GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE331nnn/GSE331114/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE331114GEOGSEfalseA skull bone marrow-glymphatic-brain axis mediates CD8 T cell trafficking and involvement in post-ischemic stroke injury 01Here, we identify a skull bone marrow (SBM)-glymphatic-brain axis that mediates the trafficking and delivery of cytotoxic CD8 T cells into the ischemic brain parenchyma in human AIS. Single-cell transcriptomic profiling of patients with AIS identifies the SBM as a dynamically responsive CD8 T cell reservoir that is transcriptionally distinct from peripheral blood.2026/05/20GSE331114GSM9739257GSM9739256GSM9739255GSM9739254GSM9739253GSM9739252GSM9739251GSM973925816791331114Homo sapiens