{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE331nnn/GSE331129/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE331129"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome profiling of colorectal tissues from AOM-induced colorectal cancer mice with cigarette smoke exposure","description":"Cigarette smoke is a known risk factor for colorectal cancer (CRC). This study investigated the mechanisms of smoke-aggravated CRC using an azoxymethane (AOM)-induced mouse model. Three groups (n=6 each) were included: control (AOM only), GF-AOM (germ-free + AOM), and GF-AOMS (germ-free + AOM + smoke exposure). Colorectal tissues were collected for RNA-seq to identify differentially expressed genes associated with smoke-mediated CRC progression.","dates":{"publication":"2026/05/20"},"accession":"GSE331129","cross_references":{"GSM":["GSM9739477","GSM9739476","GSM9739475","GSM9739474","GSM9739484","GSM9739473","GSM9739472","GSM9739483","GSM9739482","GSM9739471","GSM9739481","GSM9739470","GSM9739480","GSM9739469","GSM9739479","GSM9739468","GSM9739478","GSM9739467"],"GPL":["24247"],"GSE":["331129"],"taxon":["Mus musculus"]}}