{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE331nnn/GSE331327/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE331327"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Loss of Foxf1 in lung pericytes increases the severity of pulmonary fibrosis","description":"Multiple cell types have been implicated in pathogenesis of pulmonary fibrosis (PF) with pericytes emerging as a new focus due to their role in promoting fibrotic remodeling. Fibrotic environment changes normal pericyte functions, but transcriptional programs regulating pericyte transition towards fibrotic state remain unclear. Utilizing scRNA-seq of mouse genetic models, we identified a unique cluster of fibrosis-associated pericytes.FOXF1 was identified as one of the transcription factors decreased in fibrotic pericytes.","dates":{"publication":"2026/08/19"},"accession":"GSE331327","cross_references":{"GSM":["GSM9791957","GSM9744025"],"GPL":["34328"],"GSE":["331327"],"taxon":["Mus musculus"],"PMID":["[42373667]"]}}