GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE332nnn/GSE332646/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE332646GEOGSEfalseBulk RNA-seq of juvenile mouse liver following NDMA or saline treatment in WT and Mgmt-/- genotypes across multiple timepointsTranscriptomic profiling of mouse liver tissue to characterize the acute and long-term gene expression response to the carcinogen N-nitrosodimethylamine (NDMA) in juvenile mice. RaDR+/+;GPT+/+ (WT) and RaDR+/+;GPT+/+;Mgmt-/- (Mgmt knockout) mice received intraperitoneal injections of NDMA (3.5 mg/kg at postnatal day 8 and 7 mg/kg at postnatal day 15) or saline vehicle. Liver tissue was collected at Day 1, Day 2, Day 5, Week 10, and Month 10 post-treatment and subjected to bulk RNA-seq to identify differential gene expression patterns across genotypes, sexes, treatments, and timepoints.2026/05/22GSE332646GSM9751900GSM9751901GSM9751935GSM9751936GSM9751937GSM9751938GSM9751939GSM9751940GSM9751941GSM9751942GSM9751943GSM9751944GSM9751823GSM9751824GSM9751945GSM9751924GSM9751925GSM9751926GSM9751927GSM9751928GSM9751929GSM9751930GSM9751931GSM9751932GSM9751933GSM9751934GSM9751913GSM9751914GSM9751915GSM9751916GSM9751917GSM9751918GSM9751919GSM9751920GSM9751921GSM9751922GSM9751923GSM9751902GSM9751903GSM9751904GSM9751905GSM9751906GSM9751907GSM9751908GSM9751909GSM9751910GSM9751911GSM9751912GSM9751858GSM9751979GSM9751859GSM9751861GSM9751982GSM9751862GSM9751983GSM9751984GSM9751863GSM9751864GSM9751985GSM9751865GSM9751986GSM9751987GSM9751866GSM9751867GSM9751988GSM9751868GSM9751989GSM9752030GSM9752031GSM9752032GSM9752033GSM9752034GSM9752035GSM9751980GSM9751981GSM9752036GSM9751860GSM9751847GSM9751968GSM9751848GSM9751969GSM9751849GSM9751850GSM9751971GSM9752026GSM9752027GSM9751851GSM9751972GSM9751852GSM9751973GSM9752028GSM9751853GSM9751974GSM9752029GSM9751975GSM9751854GSM9751855GSM9751976GSM9751856GSM9751977GSM9751978GSM9751857GSM9752020GSM9752021GSM9752022GSM9752023GSM9752024GSM9751970GSM9752025GSM9751836GSM9751957GSM9751958GSM9751837GSM9751838GSM9751959GSM9751839GSM9751960GSM9752015GSM9751961GSM9752016GSM9751840GSM9751841GSM9751962GSM9752017GSM9752018GSM9751842GSM9751963GSM9751964GSM9752019GSM9751843GSM9751844GSM9751965GSM9751845GSM9751966GSM9751967GSM9751846GSM9752010GSM9752011GSM9752012GSM9752013GSM9752014GSM9751825GSM9751946GSM9751947GSM9751826GSM9751827GSM9751948GSM9751828GSM9751949GSM9751829GSM9752004GSM9751950GSM9752005GSM9751830GSM9751951GSM9752006GSM9752007GSM9751831GSM9751952GSM9751832GSM9751953GSM9752008GSM9751833GSM9751954GSM9752009GSM9751955GSM9751834GSM9751835GSM9751956GSM9752000GSM9752001GSM9752002GSM9752003GSM9751894GSM9751895GSM9751896GSM9751897GSM9751898GSM9751899GSM9751890GSM9751891GSM9751892GSM9751893GSM9751883GSM9751884GSM9751885GSM9751886GSM9751887GSM9751888GSM9751889GSM9751880GSM9751881GSM9751882GSM9751869GSM9751872GSM9751993GSM9751873GSM9751994GSM9751874GSM9751995GSM9751875GSM9751996GSM9751876GSM9751997GSM9751998GSM9751877GSM9751878GSM9751999GSM9751879GSM9751990GSM9751870GSM9751991GSM9751871GSM975199219057332646Mus musculus