GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE332nnn/GSE332663/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE332663GEOGSEfalseTranscriptomic profiling of Cosmc-silenced Tn+ 4T1 cells-bearing triple-negative tumors in miceAberrant O-glycosylation and accumulation of the Tn antigen are associated with aggressive phenotypes in triple-negative breast cancer (TNBC). To investigate the transcriptomic consequences of Tn antigen expression, we analyzed gene expression profiles of murine 4T1 breast cancer cells carrying CRISPR/Cas9-mediated silencing of the Cosmc gene (Tn+) compared with parental wild-type 4T1 cells (WT). Total RNA was extracted from 4T1 cells-bearing tumors from mice (Tn and WT)s and subjected to RNA sequencing using Illumina NovaSeq X technology.2026/06/10GSE332663GSM9752202GSM9752203GSM9752204GSM9752205GSM9752206GSM9752195GSM9752196GSM9752197GSM9752198GSM9752199GSM9752200GSM975220134328332663Mus musculus