{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE332nnn/GSE332752/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE332752"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome of mouse colon under radiation injury and syringin treatment","description":"This study performed transcriptome RNA sequencing on 15 mouse colon samples, including 5 blank control samples, 5 abdominal ionizing radiation (IR)-induced intestinal injury samples, and 5 syringin-treated injury samples. The aim was to identify gene expression changes and key regulatory pathways involved in radiation-induced intestinal damage and the protective mechanism of syringin. Differentially expressed genes (DEGs) were analyzed to explore mechanisms related to ferroptosis, the hnRNPA3-ESRRG-AIFM2-FSP1 regulatory axis, and gut-brain axis communication. These data provide a valuable transcriptomic resource for understanding radiation-induced intestinal injury and the transcriptomic responses to syringin in mouse colon tissue.","dates":{"publication":"2026/09/03"},"accession":"GSE332752","cross_references":{"GSM":["GSM9752948","GSM9752937","GSM9752936","GSM9752947","GSM9752939","GSM9752938","GSM9752940","GSM9752942","GSM9752941","GSM9752944","GSM9752943","GSM9752935","GSM9752946","GSM9752945","GSM9752934"],"GPL":["24247"],"GSE":["332752"],"taxon":["Mus musculus"]}}