{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE332nnn/GSE332759/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE332759"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Intracellular complement factor H protects neurons during CNS inflammation [bulkRNA-seq]","description":"Complement factor H (CFH) has been implicated in neuroprotection during inflammatory neurodegeneration, but its neuron-intrinsic functions remain poorly understood. Here, we performed bulk RNA sequencing of primary neuronal cultures from Cfh conditional knockout (Cfh-cKO) and control mice under basal conditions or following glutamate-induced oxidative stress. This dataset was generated to characterize transcriptional changes associated with neuronal Cfh deficiency and to identify pathways regulated by intracellular CFH during neuronal stress responses.","dates":{"publication":"2026/07/28"},"accession":"GSE332759","cross_references":{"GSM":["GSM9753017","GSM9753006","GSM9753016","GSM9753005","GSM9753019","GSM9753008","GSM9753018","GSM9753007","GSM9753009","GSM9753020","GSM9753011","GSM9753010","GSM9753013","GSM9753012","GSM9753015","GSM9753014"],"GPL":["24247"],"GSE":["332759"],"taxon":["Mus musculus"]}}