{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE333nnn/GSE333187/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE333187"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Cystine Restriction Alleviates T Cell Exhaustion and Enhances CAR-T Cell Potency","description":"This study was designed to explore how targeting Slc7a11 affected CD8+ T cell differentiation and function using a mouse colorectal cancer model. Single-cell RNA-seq was used to monitor tumor-infiltrating CD8+ T cells from Slc7a11 knockout and wild-type mouse tumor models treated with IgG control or anti-Ctla4 antibody.","dates":{"publication":"2026/07/18"},"accession":"GSE333187","cross_references":{"GSM":["GSM9758627","GSM9758626","GSM9758625","GSM9758624"],"GPL":["24247"],"GSE":["333187"],"taxon":["Mus musculus"]}}