{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE333nnn/GSE333263/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Escherichia coli"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE333263"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"SoFIC Orchestrates Physical Barriers and Metabolic Homeostasis to Counter Phage Infection","description":"Bacteria have developed numerous defense systems to counter persistent phage infections. In this study, we characterize the SoFIC defense system, consisting of a Fic family protein. Our results show that SoFIC is widely distributed across multiple bacterial phyla and contains a conserved Fic catalytic motif essential for anti-phage activity.","dates":{"publication":"2026/05/30"},"accession":"GSE333263","cross_references":{"GSM":["GSM9759935","GSM9759936","GSM9759937","GSM9759934"],"GPL":["25368"],"GSE":["333263"],"taxon":["Escherichia coli"]}}