{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE333nnn/GSE333988/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE333988"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic analysis of GKB202-treated circulating tumor cells isolated from patients with lung cancer and pancreatic cancer","description":"Circulating tumor cells (CTCs) are associated with metastatic dissemination and adaptive stress responses in cancer. In this study, patient-derived CTCs isolated from lung cancer and pancreatic cancer samples were treated with GKB202, a natural compound derived from Antrodia cinnamomea, to investigate treatment-associated transcriptomic changes. Bulk RNA sequencing was performed to compare untreated/control and GKB202-treated CTC samples. This dataset provides raw sequencing reads and processed gene-level expression matrices for evaluating the effects of GKB202 on CTC-related transcriptional programs, including stress-response and cancer-associated pathways.","dates":{"publication":"2026/06/04"},"accession":"GSE333988","cross_references":{"GSM":["GSM9778524","GSM9778523","GSM9778522","GSM9778521","GSM9778530","GSM9778529","GSM9778528","GSM9778527","GSM9778526","GSM9778525"],"GPL":["18573"],"GSE":["333988"],"taxon":["Homo sapiens"]}}