GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE334nnn/GSE334176/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE334176GEOGSEfalseTranscriptomic profiling of human corneal epithelial cells following direct contact with Pseudomonas aeruginosa or Staphylococcus epidermidisDirect interactions between microorganisms and host epithelial cells play a critical role in ocular surface homeostasis and disease. In this study, human corneal epithelial cells (HCE-2) were directly exposed to either Pseudomonas aeruginosa or Staphylococcus epidermidis. RNA sequencing was performed to characterize transcriptional changes induced by direct bacterial contact compared with untreated control cells. Article available: https://doi.org/10.3389/fcimb.2026.18991472026/08/12GSE334176GSM9782880GSM9782884GSM9782883GSM9782882GSM9782881GSM9782888GSM9782887GSM9782886GSM978288534284334176Homo sapiens10.3389/fcimb.2026.1899147