{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE334nnn/GSE334230/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE334230"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-Cell Atlas of Photoaged Skin Reveals JAK-STAT Blockade as a Strategy to Reverse Dermal Remodeling","description":"Chronic ultraviolet exposure superimposes inflammatory and matrix-degenerative insults on intrinsic aging to produce cutaneous photoaging. This study combined a chronic UVA/UVB mouse model with single-cell RNA sequencing of control, UV-exposed, and UV + ruxolitinib-treated dorsal skin to map photoaging at cellular resolution and evaluate topical JAK1/2 blockade as an intervention.","dates":{"publication":"2026/06/10"},"accession":"GSE334230","cross_references":{"GSM":["GSM9783797","GSM9783796","GSM9783795"],"GPL":["24247"],"GSE":["334230"],"taxon":["Mus musculus"]}}