GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE334nnn/GSE334500/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE334500GEOGSEfalsePsychotropic-drug and neurotransmitter perturbation RNA-seq of human iPSC-derived cardiac and retinal organoids (ToxiPred)Bulk 3'-barcoded RNA-sequencing (Drop-seq-style digital gene expression) of human iPSC-derived cardiac and retinal organoids treated for 24 h at 5 uM with psychotropic drugs (aripiprazole, loxapine, sertraline, quetiapine, xanomeline) versus a No_drug reference, each crossed with neurotransmitter / co-treatment conditions (adrenaline, dopamine, histamine, retinoic acid, serotonin) plus vehicle/chemical controls. Generated for the ToxiPred study to test predicted tissue-resolved drug liability and recover lipid/sterol pathway mechanisms.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 sapiens