GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE334nnn/GSE334586/primaryOK200TranscriptomicsHeterocephalus glaberExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE334586GEOGSEfalseTranscriptional profiling of the Epidermis of Naked Mole-RatsTreated with DMBA and TPAWe compared expressions of cancer-related genes (tumor suppressor genes and oncogenes) in the skin epidermis between Naked mole-rats treated with DMBA/TPA and control animals. Bulk RNA-seq analyses revealed that in contrast to control animals, epidermis of Naked mole-rats treated with DMBA/TPA is characterized by increased expression of anti-cancer genes, activation of genes controlling ferroptosis, as well as by downregulation of numerous oncogenes including components of NF-kB, Wnt and tyrosine kinase signaling pathways.2026/07/09GSE334586GSM9791359GSM9791360GSM9791361GSM9791356GSM9791357GSM979135821195334586Heterocephalus glaber