GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE334nnn/GSE334702/primary200OKTranscriptomicsBos taurusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE334702GEOGSEfalseEndometrial transcriptomic responses associated with a 17α-hydroxyprogesterone caproate-containing formulation and progesterone in Holstein cows: an exploratory RNA-seq analysis17α-hydroxyprogesterone caproate (17-OHPC) is included in a veterinary depot formulation approved in Japan for the prevention of implantation failure and abortion in cattle, but its molecular effects on the bovine endometrium remain unclear. In this exploratory RNA-seq study, six Holstein cattle were assigned to a 17-OHPC-containing formulation group (100 mg 17-OHPC plus 10 mg progesterone [P4]; n = 3) or a P4-alone group (100 mg P4; n = 3). Endometrial samples were collected during an untreated synchronized cycle on days 4 and 7, and during a second synchronized cycle on day 7 after treatment on day 4. RNA-seq was used to characterize treatment-associated endometrial transcriptomic profiles and gene-set enrichment patterns between the 17-OHPC/P4 formulation and P4-alone arms.2026/06/16GSE334702GSM9793824GSM9793835GSM9793823GSM9793834GSM9793826GSM9793837GSM9793836GSM9793825GSM9793828GSM9793827GSM9793829GSM9793831GSM9793820GSM9793830GSM9793833GSM9793822GSM9793821GSM979383228857334702Bos taurus