{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE335nnn/GSE335106/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335106"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Bulk RNAseq analysis of wildtype and Pim1-/- macrophages","description":"PIM1 is a serine/threonine kinase that modulates immune responses and cellular metabolism. To examine the function of PIM1 in macrophage gene expression, peritoneal macrophages were isolated from wild-type and Pim1-/- mice. They were treated with 20 μg/mL oxidized low-density lipoprotein for 8 hours. Total RNA was extracted and analyzed using bulk RNA sequencing to compare gene expression profiles and identify differentially regulated pathways between wild-type and Pim1-/- macrophages.","dates":{"publication":"2026/06/15"},"accession":"GSE335106","cross_references":{"GSM":["GSM9805890","GSM9805880","GSM9805881","GSM9805882","GSM9805883","GSM9805884","GSM9805885","GSM9805886","GSM9805887","GSM9805888","GSM9805889","GSM9805879"],"GPL":["17021"],"GSE":["335106"],"taxon":["Mus musculus"]}}