{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE335nnn/GSE335175/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335175"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Genomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas [RNA-seq]","description":"Integrated genomic characterization of meningiomas from 10 women with long-term exposure to depot medroxyprogesterone acetate (DMPA), a commonly used injectable progestin contraceptive. All tumors were newly diagnosed WHO grade 1 meningiomas. We profiled genome-wide DNA methylation (Illumina Infinium MethylationEPIC v2.0) and performed bulk RNA sequencing on all 10 tumors, and integrated these data with public reference meningioma cohorts (Baylor, GSE189521; Heidelberg, GSE109381) for methylation classifier assignment, consensus clustering, copy-number analysis, and differential methylation testing.","dates":{"publication":"2026/06/12"},"accession":"GSE335175","cross_references":{"GSM":["GSM9807640","GSM9807642","GSM9807641","GSM9807644","GSM9807643","GSM9807646","GSM9807645","GSM9807648","GSM9807647","GSM9807639"],"GPL":["30173"],"GSE":["335175"],"taxon":["Homo sapiens"]}}