GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE335nnn/GSE335175/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335175GEOGSEfalseGenomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas [RNA-seq]Integrated genomic characterization of meningiomas from 10 women with long-term exposure to depot medroxyprogesterone acetate (DMPA), a commonly used injectable progestin contraceptive. All tumors were newly diagnosed WHO grade 1 meningiomas. We profiled genome-wide DNA methylation (Illumina Infinium MethylationEPIC v2.0) and performed bulk RNA sequencing on all 10 tumors, and integrated these data with public reference meningioma cohorts (Baylor, GSE189521; Heidelberg, GSE109381) for methylation classifier assignment, consensus clustering, copy-number analysis, and differential methylation testing.2026/06/12GSE335175GSM9807640GSM9807642GSM9807641GSM9807644GSM9807643GSM9807646GSM9807645GSM9807648GSM9807647GSM980763930173335175Homo sapiens