GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE335nnn/GSE335176/primaryOK200Methylation profilingHomo sapiensMethylation profiling by genome tiling arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335176GEOGSEfalseGenomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas [methylation]Integrated genomic characterization of meningiomas from 10 women with long-term exposure to depot medroxyprogesterone acetate (DMPA), a commonly used injectable progestin contraceptive. All tumors were newly diagnosed WHO grade 1 meningiomas. We profiled genome-wide DNA methylation (Illumina Infinium MethylationEPIC v2.0) and performed bulk RNA sequencing on all 10 tumors, and integrated these data with public reference meningioma cohorts (Baylor, GSE189521; Heidelberg, GSE109381) for methylation classifier assignment, consensus clustering, copy-number analysis, and differential methylation testing.2026/06/12GSE335176GSM9807651GSM9807650GSM9807653GSM9807652GSM9807655GSM9807654GSM9807657GSM9807656GSM9807658GSM980764933022335176Homo sapiens