{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE335nnn/GSE335637/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335637"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Tumor-derived exosomal METTL3 reprograms macrophages through the m6A–IGF2BP2–ATG2A axis to promote lung adenocarcinoma stemness and brain metastasis","description":"Lung adenocarcinoma (LUAD) brain metastasis remains a major clinical challenge, yet how tumor-derived exosomes remodel macrophage states to support metastatic colonization is incompletely understood.","dates":{"publication":"2026/06/23"},"accession":"GSE335637","cross_references":{"GSM":["GSM9816559","GSM9816564","GSM9816563","GSM9816562","GSM9816561","GSM9816560"],"GPL":["24676"],"GSE":["335637"],"taxon":["Homo sapiens"]}}