GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336141/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336141GEOGSEfalseSystematic transcriptomic comparison of the time-serial interferon responses in two widely used human cell linesHere, we systematically compared the transcriptomic dynamics of IFN‑γ stimulation in HEK293T and HeLa cells across a time series (0–24 h) in duplicate. Our analysis uncovered both shared and cell‑type‑specific transcriptional responses, providing insights into the temporal regulation of interferon signaling in distinct human epithelial backgrounds.2026/07/20GSE336141GSM9828606GSM9828628GSM9828607GSM9828626GSM9828604GSM9828627GSM9828605GSM9828624GSM9828602GSM9828603GSM9828625GSM9828622GSM9828600GSM9828601GSM9828623GSM9828608GSM9828609GSM9828620GSM9828621GSM9828617GSM9828618GSM9828615GSM9828616GSM9828613GSM9828614GSM9828611GSM9828612GSM9828619GSM9828610GSM982859929480336141Homo sapiens