GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336376/primary200OKGenomicssynthetic construct Homo sapiensNon-coding RNA profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336376GEOGSEfalseIntegration of miRNA profiles and clinical data for early risk assessment of bronchopulmonary dysplasia in VLBW and ELBW newborn infants: a discovery studyBronchopulmonary dysplasia (BPD) is a major complication of preterm birth. This study aimed to identify circulating miRNA biomarkers in peripheral blood of preterm infants for early risk prediction of BPD. Peripheral blood was collected from 41 very low birth weight (VLBW) and extremely low birth weight (ELBW) preterm newborns (BPD+: n=20; BPD-: n=21) at days 10-14 of life. Total RNA was profiled using the Affymetrix GeneChip miRNA 4.1 Array (GeneTitan instrument, 96-well plate format). RMA normalization and limma differential expression identified candidate miRNA biomarkers. Four miRNAs (hsa-let-7b-5p, hsa-miR-27a-3p, hsa-let-7c-5p, hsa-miR-182-5p) were significantly upregulated in BPD infants.2026/06/30GSE336376GSM9833560GSM9833541GSM9833563GSM9833564GSM9833542GSM9833561GSM9833562GSM9833540GSM9833567GSM9833545GSM9833546GSM9833568GSM9833543GSM9833565GSM9833544GSM9833566GSM9833549GSM9833547GSM9833569GSM9833548GSM9833570GSM9833530GSM9833552GSM9833553GSM9833531GSM9833550GSM9833551GSM9833556GSM9833534GSM9833535GSM9833557GSM9833554GSM9833532GSM9833555GSM9833533GSM9833538GSM9833539GSM9833558GSM9833536GSM9833559GSM983353719117336376synthetic construct Homo sapiens