GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336578/primary200OKTranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336578GEOGSEfalseGene expression of activated CD8+ Tc1 and Tc2 cellsRNA sequencing identified distinct transcriptional programs associated with Tc2 cell metabolism, including enhanced lipid metabolism and monoamine oxidase A (MAOA)-mediated serotonin catabolism. These data provide a resource for investigating the molecular regulation of human Tc2 cells and their role in type 2 immune responses and allergic disease. Due to restrictions in participant consent and the approved EU ethical approval (Swedish Ethical Review Authority), raw sequencing data (FASTQ files) cannot be deposited in a public repository.2026/07/01GSE336578GSM9837721GSM9837720GSM9837719GSM9837718GSM9837717GSM983771618573336578Homo sapiens