{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336648/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336648"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Integrative Transcriptomics Identifies Trazodone as a Modulator of Urban Particulate Matter-Induced Neuroinflammation","description":"Urban particulate matter (UPM) triggers neuroinflammation through microglial activation, contributing to the progression of neurodegenerative diseases; however, effective therapeutic interventions remain limited. In this study, we investigated the inhibitory effects of trazodone (TZ), a clinically approved antidepressant, on UPM-induced neuroinflammation using transcriptomic analyses.","dates":{"publication":"2026/06/30"},"accession":"GSE336648","cross_references":{"GSM":["GSM9839914","GSM9839915","GSM9839916","GSM9839917","GSM9839918"],"GPL":["19057"],"GSE":["336648"],"taxon":["Mus musculus"]}}