<HashMap><database>GEO</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Other>ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336648/</Other></files><type>primary</type></body><statusCode>OK</statusCode><statusCodeValue>200</statusCodeValue></file_versions><scores/><additional><omics_type>Transcriptomics</omics_type><species>Mus musculus</species><gds_type>Expression profiling by high throughput sequencing</gds_type><full_dataset_link>https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336648</full_dataset_link><repository>GEO</repository><entry_type>GSE</entry_type></additional><is_claimable>false</is_claimable><name>Integrative Transcriptomics Identifies Trazodone as a Modulator of Urban Particulate Matter-Induced Neuroinflammation</name><description>Urban particulate matter (UPM) triggers neuroinflammation through microglial activation, contributing to the progression of neurodegenerative diseases; however, effective therapeutic interventions remain limited. In this study, we investigated the inhibitory effects of trazodone (TZ), a clinically approved antidepressant, on UPM-induced neuroinflammation using transcriptomic analyses.</description><dates><publication>2026/06/30</publication></dates><accession>GSE336648</accession><cross_references><GSM>GSM9839914</GSM><GSM>GSM9839915</GSM><GSM>GSM9839916</GSM><GSM>GSM9839917</GSM><GSM>GSM9839918</GSM><GPL>19057</GPL><GSE>336648</GSE><taxon>Mus musculus</taxon></cross_references></HashMap>