GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336756/primary200OKTranscriptomicsMus musculus OtherExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336756GEOGSEfalseCompartmentalisation of m6A (N6-methyladenosine) methylated RNA in somatic or axonal subcellular locations is dependent on Nerve Growth Factor (NGF) state in sympathetic neurons [Axon-meRIP-seq]Sympathetic neurons were culture in compartmentalised chambers in medium with NGF (control condition). Cells were then subjected to NGF starvation for 18 hours followed by 1 hour of restimulation. RNA was collected from either cell bodies (CB) or axons (Ax) from these neurons for meRIP-seq. Here, we find a strong compartmentalisation effect, in which RNA is hypermethylated in axons in both control and restimulated conditions. We also find that a select few RNA species are hypermethylated in restimulated axons compared to control axons, suggesting a fast time-dependent function for m6A marks in these RNAs.2026/07/01GSE336756GSM9841817GSM9841816GSM9841804GSM9841803GSM9841802GSM9841801GSM9841800GSM9841789GSM9841788GSM9841787GSM9841786GSM9841809GSM9841808GSM9841807GSM9841806GSM9841805GSM9841815GSM9841814GSM9841813GSM9841812GSM9841811GSM9841799GSM9841810GSM9841798GSM9841797GSM9841796GSM9841795GSM9841794GSM9841793GSM9841792GSM9841791GSM984179030172336756Mus musculus