GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337222/primary200OKMethylation profilingHomo sapiensMethylation profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337222GEOGSEfalseInternational Phase III Medulloblastoma Trial (SJMB03)Patients 3-21 years old were stratified into average-risk and high-risk treatment groups based on metastatic status and extent of resection. Medulloblastomas were molecularly classified into subgroups (Wingless [WNT], Sonic Hedgehog [SHH], group 3, and group 4) and subtypes based on DNA methylation profiles and overlaid with gene mutations from next-generation sequencing. Coprimary study end points were to assess the relationship between ERBB2 protein expression in tumors and progression-free survival (PFS), and to estimate the frequency of mutations associated with WNT and SHH tumors. Clinical and molecular risk factors were evaluated, and the most robust were used to model new risk-classification categories.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 sapiens[33405951]