{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337352/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Streptomyces coelicolor A3(2)"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337352"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"A global regulatory atlas of Streptomyces reveals conserved and diversified transcriptional networks across actinomycetes","description":"Here, we apply DNA affinity purification sequencing (DAP-seq) to 789 31 predicted TFs of Streptomyces coelicolor, generating genome-wide binding maps for 393 32 regulators and expanding the experimentally supported regulome from ~8% to ~50%. 33 Integration with ChIP-seq reveals pleiotropic regulators and hierarchical network architecture 34 linking primary metabolism, development and biosynthetic gene clusters (BGCs). This GEO data set include 11 ChIP-seq results discussed in our manuscript","dates":{"publication":"2026/07/02"},"accession":"GSE337352","cross_references":{"GSM":["GSM9853668","GSM9853669","GSM9853666","GSM9853667","GSM9853675","GSM9853665","GSM9853673","GSM9853674","GSM9853671","GSM9853672","GSM9853670"],"GPL":["37167"],"GSE":["337352"],"taxon":["Streptomyces coelicolor A3(2)"]}}