GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337352/primaryOK200GenomicsStreptomyces coelicolor A3(2)Genome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337352GEOGSEfalseA global regulatory atlas of Streptomyces reveals conserved and diversified transcriptional networks across actinomycetesHere, we apply DNA affinity purification sequencing (DAP-seq) to 789 31 predicted TFs of Streptomyces coelicolor, generating genome-wide binding maps for 393 32 regulators and expanding the experimentally supported regulome from ~8% to ~50%. 33 Integration with ChIP-seq reveals pleiotropic regulators and hierarchical network architecture 34 linking primary metabolism, development and biosynthetic gene clusters (BGCs). This GEO data set include 11 ChIP-seq results discussed in our manuscript2026/07/02GSE337352GSM9853668GSM9853669GSM9853666GSM9853667GSM9853675GSM9853665GSM9853673GSM9853674GSM9853671GSM9853672GSM985367037167337352Streptomyces coelicolor A3(2)