{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337460/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":[" Other","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337460"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Chlamydia serovars in uterus- scRNA-seq, CITE-seq and TCRab","description":"This study is part of the immgenT Open Source Project, specifically from IGT33, which focuses on characterizing T cell populations in the uterus during Chlamydia trachomatis D and L2 infections. Mice received 1% transgenic NR23.4 (CD8) and NR1 (CD4) T cells intravenously 24 hours before infection to track antigen-specific CD8 and CD4 T cell responses. Mice were infected transcervically with C. trachomatis serovars D (UW-3/Cx) and L2 (434/Bu) (5x10E6 IFU) at day 0 and rechallenged at day 28 post-infection (5x10E6 IFU). T cells were isolated from the uterus of C57BL/6J mice at multiple time points: 5 and 15 days post-primary infection and 3 and 5 days post-secondary challenge. All animals were pre-treated with medroxyprogesterone acetate to synchronize estrous cycles.","dates":{"publication":"2026/07/07"},"accession":"GSE337460","cross_references":{"GSM":["GSM9855807","GSM9855829","GSM9855828","GSM9855806","GSM9855827","GSM9855826","GSM9855825","GSM9855824","GSM9855823","GSM9855822","GSM9855821","GSM9855820","GSM9855819","GSM9855818","GSM9855817","GSM9855816","GSM9855815","GSM9855814","GSM9855813","GSM9855835","GSM9855834","GSM9855812","GSM9855833","GSM9855811","GSM9855810","GSM9855832","GSM9855831","GSM9855830","GSM9855809","GSM9855808"],"GPL":["24247"],"GSE":["337460"],"taxon":["Mus musculus"]}}