GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337539/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337539GEOGSEfalsescRNAseq of LCMV-specific P14 cells: WT, P2RX7-KO and NKG7-KOWe have used Parse Biosciences to generate single-cell RNAseq libraries from P14 CD8+ T cells (wild-type - WT, P2RX7-KO and NKG7-KO) collected from mice infected with either LCMV-Armstrong or LCMV-Clone 13 (days 0, 7 or 30 post-infection). The goal of this study was to determine the transcriptional alterations in memory or exhausted CD8+ T cells driven by the absence of either P2RX7 (a purinergic receptor that senses extracellular ATP) or NKG7 (a metabolic regulator that can downregulate mTORC1 and simultaneously induce cytotoxicity).2026/07/08GSE337539GSM9857601GSM9857602GSM9857603GSM9857604GSM9857605GSM9857606GSM9857607GSM985760834290337539Mus musculus